For the next few episodes after her forced transformation to a human, Meggy practiced for the final Splatfest to honor Desti, while finding difficulty in being human in SMG4 Movie: Meggy's Destiny. The arc ends with her being transformed into a human by The Ink Zuccer 2000, affecting her appearance in all subsequent episodes. Meggy also plays a central role in the Anime Arc.

As of SMG4: Meggy Moves In, she has moved into the Mushroom Kingdom, now residing in Belmont, Mushroom City, joining SMG4's Gang as one of its most competent and level-headed members. Although she started on poor terms with Mario when she escaped from a paint can she was trapped in, they quickly become good friends when he participates in Splatfest with her. Originally a citizen of Inkopolis, Meggy was obsessed with winning Splatfest, the top Inkling sports competition. She is a highly competitive athlete in SMG4's Gang who protects herself and her friends from danger.

Meggy Spletzer is one of the two deuteragonists (alongside Luigi) of the SMG4 series, and the main protagonist of her own spin-off series, Sunset Paradise. Meggy right after shooting Mario in SMG4: If Mario Was In. You just got REKT by the upcoming star, Meggy !